Quantitative Assessment of Polymerized and Depolymerized Platelet Microtubules
نویسندگان
چکیده
منابع مشابه
A sensitive method for measuring polymerized and depolymerized forms of tubulin in tissues
A rapid method for measuring polymerized and depolymerized forms of tubulin in tissues has been developed. The procedure consists of homogenization and centrifugation of the tissue in a microtubule-stabilizing solution and depolymerization of the precipitated microtubules; polymerized and depolymerized forms of tubulin are quantitated by a colchicine-binding assay. The validity of the technique...
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15 صفحه اولThe substructure of human platelet microtubules.
B EHNKE AND ZELANDER have recently described the filamentous substructure of platelet marginal band microtubules observed in negatively stained whole mount preparations.”2 Each microtubule was composed of up to 12 evenly spaced 35 A#{176} subfilaments in parallel association. Beading of the subfilaments was observed, but a relationship of beads on adjacent subfilaments was not commented upon. A...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1979
ISSN: 0021-9738
DOI: 10.1172/jci109321